Prophylaxis in patients with aniridia is directed toward the prevention of glaucoma, which includes the following: Medical treatment with miotics Surgical separation of the iris from the trabecular meshwork in selected cases Limbal stem cell deficiency associated with aniridia can be treated with the following: Lubricating drops Topical steroid pulses Vitamin A ointments Autologous serum drops Topical bevacizumab drops have been reported in one study. [18] Limbal stem cell transplantation The medical treatment of aniridia is directed toward control of intraocular pressure, which includes the topical use of the following: Miotics Beta-blockers Sympathomimetics Carbonic anhydrase inhibitors Prostaglandin analogues The chances of failure with local antiglaucoma treatment are high. Treatment of photophobia and nystagmus in patients with aniridia is as follows: Tinted or iris contact lenses Tinted spectacle lenses Tinted intraocular lenses (IOLs) [19] By the above measures, reducing the amplitude and frequency of nystagmus is possible.