This is somewhat a misnomer because there is always some amount of iris tissue present. This condition commonly presents with other ocular problems that involve the other parts of the eye such as cataract, lens subluxation, glaucoma, optic nerve hypoplasia, and foveal hypoplasia. The latter two results in poor vision.
Prophylaxis in patients with aniridia is directed toward the prevention of glaucoma, which includes the following:
Medical treatment with miotics
Surgical separation of the iris from the trabecular meshwork in selected cases
Limbal stem cell deficiency associated with aniridia can be treated with the following:
Topical steroid pulses
Vitamin A ointments
Autologous serum drops
Topical bevacizumab drops
Limbal stem cell transplantation
The medical treatment of aniridia is directed toward control of intraocular pressure, which includes the topical use of the following:
Carbonic anhydrase inhibitors
The chances of failure with local antiglaucoma treatment are high.
Treatment of photophobia and nystagmus in patients with aniridia is as follows:
Tinted or iris contact lenses
Tinted spectacle lenses
Tinted intraocular lenses (IOLs)
By the above measures, reducing the amplitude and frequency of nystagmus is possible.
Dr. Barbara Roque is a an ophthalmologist whose practice includes general ophthalmology (which includes cataract surgery) with subspecialty work in pediatric ophthalmology, strabismus and ophthalmic genetics.
ROQUE Eye Clinic Featured Image Eyelid Lump Chalazion or Hordeolum