PRICE
LOCATION
Corneal Collagen Cross-Linking strengthens a weak cornea and helps stop keratoconus from getting worse. The treatment uses vitamin eye drops and safe ultraviolet light to stabilize corneal structure. Early intervention improves long-term outcomes and reduces the risk of severe vision distortion.
Dr. Manolette Roque | Dr. Barbara Roque
St. Luke’s Medical Center – Global City
2nd Floor, Units 217-218, Roque Eye Clinic, Medical Arts Building
Rizal Drive cor. 5th Ave, Taguig City 1634, Philippines
+63-917-844-2020
+63-998-998-2020
+63-2-8828-2020
+63-2-8789-7700 ext. 7217
+63-2-8789-7700 ext. 7218
DETAILS
OVERVIEW
Corneal Collagen Cross-Linking is a clinically proven medical procedure designed to strengthen the cornea, the clear front window of the eye. It is primarily used to slow or stop the progression of corneal weakening conditions such as keratoconus and post-refractive surgery corneal instability. By reinforcing the natural structure of the cornea, this treatment helps preserve vision and reduce the risk of future vision loss.
HOW THE PROCEDURE WORKS
During Corneal Collagen Cross-Linking, riboflavin (vitamin B2) eye drops are applied to the cornea. Next, a controlled ultraviolet-A light activates the riboflavin. As a result, new bonds form between collagen fibers within the cornea. These additional bonds increase corneal strength and stability, much like reinforcing weakened beams in a structure. Therefore, the cornea becomes more resistant to further bulging or distortion.
WHO MAY BENEFIT
This procedure is recommended for patients with documented progression of keratoconus, corneal ectasia, or corneal thinning after laser vision correction. It is especially beneficial for younger patients, since corneal weakening often progresses more rapidly at an early age. However, suitability is always determined after a comprehensive eye examination and detailed corneal imaging.
EXPECTED BENEFITS
The primary goal of Corneal Collagen Cross-Linking is to halt disease progression rather than to eliminate the need for glasses or contact lenses. In many patients, vision stabilizes, and in some cases, mild improvement in corneal shape and vision may occur. Most importantly, early treatment can delay or prevent the need for more invasive procedures, such as corneal transplantation.
SAFETY AND RECOVERY
Corneal Collagen Cross-Linking is supported by extensive clinical research and international practice guidelines. When performed with proper screening and technique, it has a strong safety profile. After the procedure, temporary discomfort, light sensitivity, and blurred vision are expected. Nonetheless, these symptoms usually improve within days to weeks. Regular follow-up visits ensure proper healing and long-term stability.
WHY PROFESSIONAL EVALUATION MATTERS
Although the procedure is standardized, careful patient selection and customized planning are essential. Factors such as corneal thickness, disease stage, and overall eye health must be assessed. Therefore, treatment is always preceded by a thorough evaluation using advanced diagnostic tools to ensure safety and effectiveness.
LONG-TERM OUTLOOK
Corneal Collagen Cross-Linking addresses the underlying biomechanical weakness of the cornea. While it does not cure keratoconus, it plays a crucial role in preserving functional vision and protecting long-term eye health. With timely intervention and appropriate monitoring, many patients maintain stable vision for years.









